·        Mechanisms of T cell responses to DNA vaccines encoding proteins of influenza viruses, hepatitis C , tumor-associated antigens.

·        Regulation of expression of the target protein encoded by a DNA vector.

·        Cancer killing dendritic cells and macrophages - induction and effector mechanisms

·        Reprogramming of cancer-promoting dendritic cells and macrophages into cancer killer cells

·        Tumor immunotherapy, overcoming immunosuppression

·        The mathematical model of dynamics of a dividing cell population

·        How immune cells integrate external signals: experiment and mathematical model

·        The proprietary pharmaceutical grade TLR4 agonist - structure and mechanisms of action

·        Synthetic peptides of ezrin hinge region as regulators of inflammation phases: mechanism of action and clinical applications

Acta Naturae. 2014 Oct;6(4):27-39.

Regulation of the target protein (transgene) expression in the adenovirus vector using agonists of toll-like receptors.

Bagaev AV1, Pichugin AV1, Lebedeva ES1, Lysenko AA2, Shmarov MM2, Logunov DY2, Naroditsky BS2, Ataullakhanov RI1, Khaitov RM1, Gintsburg AL2.

FIELDS OF RESEARCH

RECENT PUBLICATIONS

COLLABORATIONS

J Transl Med. 2014; 12: 322. Published online 2014 Nov 29. doi:  10.1186/s12967-014-0322-yPMCID: PMC4261251

Targeting TLR-4 with a novel pharmaceutical grade plant derived agonist,Immunomax®, as a therapeutic strategy for metastatic breast cancer

Anahit Ghochikyan, Alexey Pichugin, Alexander Bagaev, Arpine Davtyan, Armine Hovakimyan, Amir Tukhvatulin,Hayk Davtyan, Dmitry Shcheblyakov, Denis Logunov, Marina Chulkina, Anastasia Savilova, Dmitry Trofimov, Edward L Nelson, Michael G Agadjanyan, and Ravshan I Ataullakhanov

Fazly Ataullakhanov labs

http://www.fazly.ru/

 

Michael G Agadjanyan lab

http://www.immun-immed.org/default.html

 

Boris Naroditsky lab

http://www.gamaleya.ru/

 

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Редактирование генома с помощью CRISPR/Cas в иммунологии и вирусологии: от нокаута гена до регуляции экспрессии

Сегодня стали доступны к просмотру виодеозаписи семинаров 2008 года! В том числе лекция памяти Е.А. Гурвича. Посмотреть их можно нажав на новость, либо из вкладки семинары > архив видеозаписей.