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· Regulation of expression of the target protein encoded by a DNA vector.
· Cancer killing dendritic cells and macrophages - induction and effector mechanisms
· Reprogramming of cancer-promoting dendritic cells and macrophages into cancer killer cells
· Tumor immunotherapy, overcoming immunosuppression
· The mathematical model of dynamics of a dividing cell population
· How immune cells integrate external signals: experiment and mathematical model
· The proprietary pharmaceutical grade TLR4 agonist - structure and mechanisms of action
· Synthetic peptides of ezrin hinge region as regulators of inflammation phases: mechanism of action and clinical applications
Редактирование генома с помощью CRISPR/Cas в иммунологии и вирусологии: от нокаута гена до регуляции экспрессии
Сегодня стали доступны к просмотру виодеозаписи семинаров 2008 года! В том числе лекция памяти Е.А. Гурвича. Посмотреть их можно нажав на новость, либо из вкладки семинары > архив видеозаписей.
RECENT PUBLICATIONS
Acta Naturae. 2014 Oct;6(4):27-39.
Regulation of the target protein (transgene) expression in the adenovirus vector using agonists of toll-like receptors.
Bagaev AV1, Pichugin AV1, Lebedeva ES1, Lysenko AA2, Shmarov MM2, Logunov DY2, Naroditsky BS2, Ataullakhanov RI1, Khaitov RM1, Gintsburg AL2.
J Transl Med. 2014; 12: 322. Published online 2014 Nov 29. doi: 10.1186/s12967-014-0322-yPMCID: PMC4261251
Targeting TLR-4 with a novel pharmaceutical grade plant derived agonist,Immunomax®, as a therapeutic strategy for metastatic breast cancer
Anahit Ghochikyan, Alexey Pichugin, Alexander Bagaev, Arpine Davtyan, Armine Hovakimyan, Amir Tukhvatulin,Hayk Davtyan, Dmitry Shcheblyakov, Denis Logunov, Marina Chulkina, Anastasia Savilova, Dmitry Trofimov, Edward L Nelson, Michael G Agadjanyan, and Ravshan I Ataullakhanov
COLLABORATIONS
Fazly Ataullakhanov labs
Michael G Agadjanyan lab
http://www.immun-immed.org/default.html
Boris Naroditsky lab